StacksVerified U.S. regulatory reference

15 CFR Part 712, Supplement No. 1

Verified against eCFR.gov as of June 20, 2026View official text on eCFR.gov

| CASregistry No.

A. Toxic Chemicals: |

1. Family: O-Alkyl(≤C10, incl. cycloalkyl) alkyl (Me, Et, n-Pr or i-Pr)- phosphonofluoridates |

Not limited to the following examples: |

Sarin: O-Isopropyl methylphosphonofluoridate107-44-8
Soman: O-Pinacolyl methylphosphonofluoridate96-64-0

2. Family: O-Alkyl (≤C10, incl. cycloalkyl) N,N-dialkyl (Me, Et, n-Pr or i-Pr) phosphoramidocyanidates |

Not limited to the following example: |

Tabun: O-Ethyl N,N-dimethyl phosphoramidocyanidate | 77-81-6

3. Family: O-Alkyl (H or ≤C10, incl. cycloalkyl) S-2-dialkyl (Me, Et, n-Pr or i-Pr)-aminoethyl alkyl (Me, Et, n-Pr or i-Pr) phosphonothiolates and corresponding alkylated or protonated salts |

Not limited to the following example: |

VX: O-Ethyl S-2-diisopropylaminoethyl methyl phosphonothiolate | 50782-69-9

4. Sulfur mustards: |

2-Chloroethylchloromethylsulfide2625-76-5
Mustard gas: Bis(2-chloroethyl)sulfide505-60-2
Bis(2-chloroethylthio)methane63869-13-6
Sesquimustard: 1,2-Bis(2-chloroethylthio)ethane3563-36-8
1,3-Bis(2-chloroethylthio)-n-propane63905-10-2
1,4-Bis(2-chloroethylthio)-n-butane142868-93-7
1,5-Bis(2-chloroethylthio)-n-pentane142868-94-8
Bis(2-chloroethylthiomethyl)ether63918-90-1
O-Mustard: Bis(2-chloroethylthioethyl)ether63918-89-8

5. Lewisites: |

Lewisite 1: 2-Chlorovinyldichloroarsine541-25-3
Lewisite 2: Bis(2-chlorovinyl)chloroarsine40334-69-8
Lewisite 3: Tris(2-chlorovinyl)arsine40334-70-1

6. Nitrogen mustards: |

HN1: Bis(2-chloroethyl)ethylamine538-07-8
HN2: Bis(2-chloroethyl)methylamine51-75-2
HN3: Tris(2-chloroethyl)amine555-77-1
7. Saxitoxin35523-89-8
8. Ricin9009-86-3

13. Family: Р-alkyl (H or ≤C10, incl. cycloalkyl) N-(1-(dialkyl(≤C10, incl. cycloalkyl)amino))alkylidene(H or ≤C10, incl. cycloalkyl) phosphonamidic fluorides and corresponding alkylated or protonated salts |

Not limited to the following examples: |

N-(1-(di-n-decylamino)-n-decylidene)-P-decylphosphonamidic fluoride2387495-99-8
Methyl-(1-(diethylamino)ethylidene)phosphonamidofluoridate2387496-12-8

14. Family: O-alkyl (H or ≤C10, incl. cycloalkyl) N-(1-(dialkyl(≤C10, incl. cycloalkyl)amino))alkylidene(H or ≤C10, incl. cycloalkyl) phosphoramidofluoridates and corresponding alkylated or protonated salts |

Not limited to the following examples: |

O-n-Decyl N-(1-(di-n-decylamino)-n decylidene)phosphoramidofluoridate2387496-00-4
Methyl (1-(diethylamino)ethylidene)phosphoramidofluoridate2387496-04-8
Ethyl (1-(diethylamino)ethylidene)phosphoramidofluoridate2387496-06-0
15. Methyl-(bis(diethylamino)methylene)phosphonamidofluoridate2387496-14-0

16. Carbamates (quaternaries and bisquaternaries of dimethylcarbamoyloxypyridines) |

16.1. Family: Quaternaries of dimethylcarbamoyloxypyridines: 1-[N,N-dialkyl(≤C10)-N-(n-(hydroxyl, cyano, acetoxy)alkyl(≤C10)) ammonio]-n-[N-(3-dimethylcarbamoxy-α-picolinyl)-N,N-dialkyl(≤C10) ammonio]decane dibromide (n=1-8) |

Not limited to the following example: |

1-[N,N-dimethyl-N-(2-hydroxy)ethylammonio]-10-[N-(3-dimethylcarbamoxy-α-picolinyl)-N,N-dimethylammonio]decane dibromide | 77104-62-2

16.2. Family: Bisquaternaries of dimethylcarbamoyloxypyridines:1,n-Bis[N-(3-dimethylcarbamoxy-α-picolyl)-N,N-dialkyl(≤C10) ammonio]-alkane-(2,(n-1)-dione) dibromide (n=2-12) |

Not limited to the following example: |

1,10-Bis[N-(3-dimethylcarbamoxy-α-picolyl)-N-ethyl-N- methylammonio]decane-2,9-dione dibromide | 77104-00-8

B. Precursors: |

9. Family: Alkyl (Me, Et, n-Pr or i-Pr) phosphonyldifluorides |

Not limited to the following example: |

DF: Methylphosphonyldifluoride | 676-99-3

10. Family: O-Alkyl (H or ≤C10, incl. cycloalkyl) O-2-dialkyl (Me, Et, n-Pr or i-Pr)-aminoethyl alkyl (Me, Et, n-Pr or i-Pr) phosphonites and corresponding alkylated or protonated salts |

Not limited to the following example: |

QL: O-Ethyl O-2-diisopropylaminoethyl methylphosphonite57856-11-8
11. Chlorosarin: O-Isopropyl methylphosphonochloridate1445-76-7
12. Chlorosoman: O-Pinacolyl methylphosphonochloridate7040-57-5

Notes to Supplement No. 1

Note 1: Note that the following Schedule 1 chemicals are controlled for export purposes under the Export Administration Regulations (see part 774 of the EAR, the Commerce Control List): Saxitoxin (35523-89-8) and Ricin (9009-86-3).

Note 2: All Schedule 1 chemicals not listed in Note 1 to this Supplement are controlled for export purposes by the Directorate of Defense Trade Controls of the Department of State under the International Traffic in Arms Regulations (22 CFR parts 120 through 130).

Note 3: The numerical sequence of the “Schedule 1” Toxic Chemicals and Precursors is not consecutive so as to align with the December 23, 2019, consolidated textual changes to “Schedule 1” of the Annex on Chemicals to the Chemical Weapons Convention (CWC), which reflect the decisions adopted by the CWC Conference of the States Parties in November 2019.

[71 FR 24929, Apr. 27, 2006, as amended at 86 FR 941, Jan. 7, 2021]