StacksVerified U.S. regulatory reference

21 CFR §170.245

Verified against eCFR.gov as of June 20, 2026View official text on eCFR.gov
If the statutory basis for your conclusion of GRAS status is through experience based on common use in food, in Part 5 of your GRAS notice you must include evidence of a substantial history of consumption of the notified substance for food use by a significant number of consumers prior to January 1, 1958.