StacksVerified U.S. regulatory reference

21 CFR §556.344

Verified against eCFR.gov as of June 20, 2026View official text on eCFR.gov ↗
  1. (a)Acceptable daily intake (ADI). The ADI for total residue of ivermectin is 5 µg/kg of body weight per day.
  2. (b)Tolerances. The tolerances for 22,23-dihydroavermectin B1a (marker residue) are:
    1. (1)American bison. Liver (target tissue): 15 ppb.
    2. (2)Cattle.
      1. (i)Liver (target tissue): 1.6 ppm.
      2. (ii)Muscle: 650 ppb.
    3. (3)Reindeer. Liver (target tissue): 15 ppb.
    4. (4)Sheep. Liver (target tissue): 30 ppb.
    5. (5)Swine.
      1. (i)Liver (target tissue): 20 ppb.
      2. (ii)Muscle: 20 ppb.
  3. (c)Related conditions of use. See §§ 520.1192, 520.1195, 520.1197, 522.1192, 522.1193, 524.1193, and 558.300 of this chapter.