21 CFR §558.325

1. (a)Specifications. Type A medicated articles containing 20 or 50 grams of lincomycin (as lincomycin hydrochloride) per pound.
2. (b)Sponsor. See No. 054771 in § 510.600(c) of this chapter.
3. (c)Related tolerances. See § 556.360 of this chapter.
4. (d)Special considerations.
   1. (1)Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.
   2. (2)The expiration date of VFDs for lincomycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for lincomycin shall not be refilled.
   3. (3)Labeling of Type A medicated articles and Type B and Type C medicated feeds containing lincomycin shall bear the following:
      1. (i)“CAUTION: Do not allow rabbits, hamsters, guinea pigs, horses, or ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects.”
      2. (ii)[Reserved]
   4. (4)Labeling of medicated feeds containing lincomycin intended for use in swine shall bear the following:
      1. (i)“CAUTION: Occasionally, swine fed lincomycin may within the first 2 days after the onset of treatment develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may show reddening of the skin and irritable behavior. These conditions have been self-correcting within 5 to 8 days without discontinuing the lincomycin treatment.”
      2. (ii)“CAUTION: The effects of lincomycin on swine reproductive performance, pregnancy, and lactation have not been determined.”
5. (e)Conditions of use—(1) Chickens—
   1. (2)Swine—