45 CFR §1321.89

1. (a)Evidence-based disease prevention and health promotion services programs are community-based interventions as set forth in Title III, part D of the Act, that have been proven to improve health and well-being and/or reduce risk of injury, disease, or disability among older adults. All programs provided using these funds must be evidence-based and must meet the Act's requirements and guidance as set forth by the Assistant Secretary for Aging.
2. (b)All funds provided under Title III, part D of the Act must be distributed within a State pursuant to § 1321.49 or § 1321.51.