(a) Specifications. Type A medicated articles containing 10, 20, 50, or 227 grams virginiamycin per pound.

(b) Sponsors. See No. 066104 in §510.600(c) of this chapter.

(c) Related tolerances. See §556.750 of this chapter.

(d) Special considerations.

(1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See §558.6 for additional requirements.

(2) The expiration date of VFDs for virginiamycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for virginiamycin shall not be refilled.

(3) Not for use in breeding swine over 120 pounds.

(4) Dilute Type A article with at least 10 pounds of a feed ingredient prior to final mixing in 1 ton of Type C feed.

(e) Conditions of use—(1) Chickens

Open Table
Virginiamycin
grams/ton
Combination in grams/ton Indications for use Limitations Sponsors
(i) 20 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin Not for use in layers 066104
(ii) 20 Amprolium 72.6 to 113.5 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis caused by Eimeria tenella For field conditions where only E. tenella is the major problem, feed continuously as the sole ration. Use as the sole source of amprolium. Do not use in feeds containing bentonite. Not for use in laying chickens. Amprolium as provided by No. 016592 in §510.600(c) of this chapter 066104
(iii) 20 Amprolium 113.5 to 227 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis where immunity to coccidiosis is not desired For most field conditions as they exist under modern management practices, feed 113.5 g/ton amprolium continuously. Where severe coccidiosis conditions exist, feed 227 g/ton. Use as the sole source of amprolium. Do not use in feeds containing bentonite. Not for use in laying chickens. Amprolium as provided by No. 016592 in §510.600(c) of this chapter 066104
(iv) 20 Diclazuril 0.91 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. brunetti, E. mitis (mivati), and E. maxima. Because diclazuril is effective against E. maxima late in its life cycle, subclinical intestinal lesions may be present for a short time after infection. Diclazuril was shown in studies to reduce lesions scores and improve performance and health of birds challenged with E. maxima Feed continuously as the sole ration. Do not use in hens producing eggs for human food. Diclazuril as provided by No. 058198 in §510.600(c) of this chapter 058198
(v) 20 Lasalocid 68 to 113 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. brunetti, E. mivati, and E. maxima Feed continuously as the sole ration. Do not feed to laying chickens. For broiler or fryer chickens only. Lasalocid as provided by No. 054771 in §510.600(c) of this chapter 066104
(vi) 20 Monensin 90 to 110 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and as an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. maxima, and E. mivati Feed continuously as the sole ration. Do not feed to laying chickens. See §558.355(d) in this chapter. Monensin as provided by No. 058198 in §510.600(c) of this chapter 066104
(vii) 20 Salinomycin 40 to 60 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati Feed continuously as the sole ration. Do not feed to chickens over 16 weeks of age. Do not feed to laying chickens. Not approved for use with pellet binders. May be fatal if accidentally fed to adult turkeys or horses. Salinomycin as provided by No. 016592 in §510.600(c) of this chapter
(viii) 20 Semduramicin 22.7 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis caused by Eimeria acervulina, E. brunetti, E. maxima, E mivati/mitis, E. necatrix, and E. tenella Feed continuously as the sole ration. Do not feed to laying hens. Semduramicin as provided by No. 066104 in §510.600(c) of this chapter 066104
(ix) 20 Semduramicin (biomass) 22.7 Broiler chickens: For prevention of necrotic enteritis caused by Clostridium perfringens susceptible to virginiamycin; and for the prevention of coccidiosis caused by Eimeria acervulina, E. brunetti, E. maxima, E mivati/mitis, E. necatrix, and E. tenella Feed continuously as the sole ration. Withdraw 1 day before slaughter. Do not feed to laying hens. Semduramicin as provided by No. 066104 in §510.600(c) of this chapter 066104

(2) Swine

Open Table
Virginiamycin grams/ton Combination in grams/ton Indications for use Limitations Sponsor
(i) 25 Growing-finishing swine: As an aid in control of dysentery in swine up to 120 pounds in animals or on premises with a history of swine dysentery but where symptoms have not yet occurred 066104
(ii) 50 or 100 Growing-finishing swine: For treatment and control of swine dysentery in swine up to 120 pounds Feed 100 grams per ton for 2 weeks, 50 grams per ton thereafter 066104
(iii) 100 Growing-finishing swine: For treatment of swine dysentery in nonbreeding swine over 120 pounds Feed for 2 weeks 066104

(3) Cattle

Open Table
Virginiamycin grams/ton Combination in grams/ton Indications for use Limitations Sponsor
(i) 13.5 to 16.0 Cattle fed in confinement for slaughter: For reduction of incidence of liver abscesses Feed continuously as the sole ration to provide 85 to 240 milligrams per head per day. Not for use in animals intended for breeding 066104
(ii) [Reserved]

[81 FR 95022, Dec. 27, 2016, as amended at 82 FR 11512, Feb. 24, 2017; 82 FR 21692, May 10, 2017; 85 FR 18125, Apr. 1, 2020]


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