StacksVerified U.S. regulatory reference

21 CFR §172.580

Verified against eCFR.gov as of June 20, 2026View official text on eCFR.gov ↗
The food additive safrole-free extract of sassafras may be safely used in accordance with the following prescribed conditions:
  1. (a)The additive is the aqueous extract obtained from the root bark of the plant Sassafras albidum (Nuttall) Nees (Fam. Lauraceae).
  2. (b)It is obtained by extracting the bark with dilute alcohol, first concentrating the alcoholic solution by vacuum distillation, then diluting the concentrate with water and discarding the oily fraction.
  3. (c)The purified aqueous extract is safrole-free.
  4. (d)It is used as a flavoring in food.