CFR › Title 21 › Part 182 › §182.118021 CFR §182.1180Verified against eCFR.gov as of June 20, 2026View official text on eCFR.gov ↗Copy link(a)Product. Caffeine.(b)Tolerance. 0.02 percent.(c)Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in cola-type beverages in accordance with good manufacturing practice.