40 CFR §68.77

1. (a)The owner or operator shall perform a pre-startup safety review for new stationary sources and for modified stationary sources when the modification is significant enough to require a change in the process safety information.
2. (b)The pre-startup safety review shall confirm that prior to the introduction of regulated substances to a process:
   1. (1)Construction and equipment is in accordance with design specifications;
   2. (2)Safety, operating, maintenance, and emergency procedures are in place and are adequate;
   3. (3)For new stationary sources, a process hazard analysis has been performed and recommendations have been resolved or implemented before startup; and modified stationary sources meet the requirements contained in management of change, § 68.75.
   4. (4)Training of each employee involved in operating a process has been completed.