40 CFR §710.27

1. (a)In general. The following activities do not trigger notification requirements under this subpart:
   1. (1)The manufacturing or processing of a chemical substance in small quantities solely for research and development.
   2. (2)The import or processing of a chemical substance as part of an article.
   3. (3)The manufacturing or processing of a chemical substance as described in § 720.30(g) or (h).
   4. (4)The manufacturing or processing of a chemical substance solely for export from the United States as described in § 720.30(e) or § 721.3, except where the Administrator has made a finding described in TSCA section 12(a)(2).
   5. (5)The manufacturing or processing of a chemical substance solely for test marketing purposes.
2. (b)Manufacturing or processing naturally occurring chemical substances. The following activities do not trigger notification requirements under this subpart:
   1. (1)The manufacture of a naturally occurring chemical substance, as described in § 710.4(b). Some chemical substances can be manufactured both as described in § 710.4(b) and by means other than those described in § 710.4(b). If a person manufactures a chemical substance by means other than those described in § 710.4(b), this exemption is inapplicable, regardless of whether the chemical substance also could have been produced as described in § 710.4(b). This exemption does not cover the manufacture of a chemical substance from a naturally occurring chemical substance.
   2. (2)The processing of a naturally occurring chemical substance only by manual, mechanical, or gravitational means; by dissolution in water; by flotation; or by heating solely to remove water.