42 CFR §81.25

Verified against eCFR.gov as of June 20, 2026View official text on eCFR.gov ↗

For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated probability of causation for each cancer individually. Then DOL will perform the following calculation using the probability of causation estimates produced by NIOSH-IREP: